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Recombinant Human VEGF165
名稱 Recombinant Human VEGF165
型號
更新時間 2023-09-24
特點 VEGF是一個強有力的增長和血管生成細胞因子。它刺激內皮細胞的增殖和生存,促進血管生成和血管通透性。用血管化組織中表達,VEGF在正常和病理血管生成中起著重要的作用。重組人類VEGF是38.2 kDa disulfide-linked homodimeric兩個165個氨基酸組成的蛋白質多肽鏈。使用所有無動物生產試劑。}
  • 詳細內容

一.產品名稱:Recombinant Human VEGF165

二.Catalog Number:AF-100-20

三.Synonyms:

Vascular Endothelial Growth Factor, VPF, Folliculoslate cell-derived growth factor, Glioma-derived endothelial cell mitogen

四.Description:

VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant human VEGF is a 38.2 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains. Manufactured using all non-animal reagents.

五.AA Sequence:

APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR

六.Source:E.coli

七.Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.

八.Biological Activity:

Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-8.0 ng/ml.

九.Cross Reactivity:

Cow, Green Algae, Guinea Pig, Hamster, Mouse, Pig, Rabbit, Rat, Sheep, Trout, Human

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