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Recombinant Human GM-CSF
名稱 Recombinant Human GM-CSF
型號
更新時間 2023-09-24
特點 GM-CSF的造血生長因子刺激中性粒細胞和巨噬細胞的發展和促進早期的擴散和發展紅色的巨核細胞和嗜酸性粒細胞的祖細胞。生產的內皮細胞,單核細胞、成纖維細胞和淋巴細胞。gm - csf抑制中性粒細胞遷移和增強的功能活動end-cells成熟。人類和小鼠分子具有種特異性,表現出沒有跨物種反應性。}
  • 詳細內容

一.產品名稱:Recombinant Human GM-CSF

二.產地:Peprotech公司

三.貨號Catalog Number:AF-300-03

四.同義Synonyms:Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-alpha

五.描述Description:

GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant human GM-CSF is a 14.6 kDa globular protein consisting of 128 amino acids containing two intramolecular disulfide bonds and two potential N-linked glycosylation sites. Manufactured using all non-animal reagents.

六.AA序列AA Sequence:

MAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE

七.來源Source:E.coli

八.純度Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.

九.活性Biological Activity:

The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.

十.交叉性Cross Reactivity:Human, Mouse

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